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/IONS
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Ionis Pharmaceuticals Inc

Ionis Pharmaceuticals Inc

IONS
$54.21USD-2.59%-1.44 today

MARKET CAP

9.0B

P/E (TTM)

FWD P/E

DAY RANGE

$54 – $56

52W RANGE

$50
$87

AI Summary

Stalk
StalkMedium

IONS remains below its 50-day and 200-day SMAs after a post-capitulation rally, showing medium-term bullish potential but recent exhaustion at resistance warrants patience. We will stalk for a pullback into the rising 9- and 20-day EMAs to confirm structural support before engaging. Primary downside risk is a break below the 9-day EMA, which would signal deeper weakness.

  • ZANVASTRO FDA approval could drive >$100M peak sales.
  • Tringolza Q2 revenue surged 3× to $19M.
  • Non-GAAP op losses of $425–475M challenge profitability targets.
Full analysis →

Buying

7

institutions

Selling

10

institutions

New Positions

0

this quarter

Filing Period

Q2 2026

latest 13-F

13-F Holdings

InstitutionActionShares HeldValueChangeChg %Weight
BI

Blackrock, Inc.

Q2 2026

BUY10.70 M848.77 M+262.18 K+8.2%0.01%
TR

T. Rowe Price Investment Management, Inc.

Q2 2026

SELL3.96 M313.94 M+-2.20 M-32.1%0.21%
JC

Jpmorgan Chase & Co

Q2 2026

BUY2.67 M216.20 M+308.15 K+26.1%0.01%
CA

Citadel Advisors LLC

Q2 2026

SELL855.28 K67.82 M+-450.85 K-30.9%0.01%
EP

Eversept Partners, LP

Q2 2026

BUY664.68 K52.70 M+32.58 K+11.0%2.73%
VI

Voloridge Investment Management, LLC

Q2 2026

SELL655.45 K51.97 M+-17.40 K+2.9%0.22%
PA

Perceptive Advisors LLC

Q2 2026

SELL566.00 K44.88 M+-442.00 K-40.7%0.68%
RT

Renaissance Technologies LLC

Q2 2026

BUY559.41 K44.36 M+253.87 K+93.3%0.06%
MM

Millennium Management LLC

Q2 2026

SELL546.37 K43.32 M+-505.13 K-45.1%0.02%
CP

California Public Employees Retirement System

Q2 2026

BUY270.84 K21.48 M+15.36 K+11.9%0.01%
AC

Adar1 Capital Management, LLC

Q2 2026

BUY166.29 K13.18 M+5.95 K+9.5%0.61%
FA

Fisher Asset Management, LLC

Q2 2026

SELL137.18 K10.88 M+-4.36 K+2.3%0.00%
JH

Janus Henderson Group Plc

Q1 2026

BUY136.38 K10.24 M+68.19 K+89.8%0.00%
PA

Point72 Asset Management, L.P.

Q2 2026

SELL34.20 K2.71 M+-2.90 K-2.7%0.00%
AC

Aqr Capital Management LLC

Q2 2026

SELL22.06 K1.75 M+-6.72 K-19.1%0.00%
MG

Man Group Plc

Q2 2026

SELL12.36 K980.10 K+-11.65 K-45.6%0.00%
RC

Rockefeller Capital Management L.P.

Q2 2026

SELL3.83 K303.84 K+-323.00-2.6%0.00%