/SEPN

Septerna Inc

SEPN

$38.51USD↑+2.01%+0.76 today

MARKET CAP

1.8B

P/E (TTM)

—

FWD P/E

—

DAY RANGE

$38 – $40

52W RANGE

$14

$51

AI Summary

Stalk

StalkMedium

SEPN remains in a Stage 2 uptrend but is consolidating between its 9/20 EMAs and the 50-day SMA. Short-term momentum is neutral, and price is holding above the rising 50-day SMA. A disciplined pullback entry into support is preferred, awaiting clear re-acceleration above the 20-day EMA before committing.

↑Unanimous buy consensus across 10 analysts; $45.00 avg. target (+27.9%)
↑SEP-479 preclinical results show promising PTH1R agonist progress
↓Q2 EPS forecast at -$0.426; Q1 EPS exceeded estimates at -$0.19

Full analysis →

Buying

9

institutions

Selling

4

institutions

New Positions

4

this quarter

Filing Period

Q1 2026

latest 13-F

13-F Holdings

Institution↕	Action↕	Shares Held↕	Value↓	Change↕	Chg %↕	Weight↕
BI Blackrock, Inc. Q2 2026	BUY	1.93 M	64.71 M	+109.91 K	+47.8%	0.00%
JH Janus Henderson Group Plc Q1 2026	BUYNEW	1.78 M	42.67 M	+1.78 M	+0.0%	0.01%
AC Adar1 Capital Management, LLC Q2 2026	SELL	940.75 K	31.51 M	+-149.07 K	+20.3%	1.45%
BA Balyasny Asset Management L.P. Q2 2026	BUY	350.44 K	11.74 M	+113.76 K	+106.4%	0.01%
WP Woodline Partners LP Q2 2026	BUYNEW	185.53 K	6.21 M	+185.53 K	+0.0%	0.02%
JC Jpmorgan Chase & Co Q2 2026	BUY	85.30 K	2.96 M	+627.00	+50.3%	0.00%
CA Citadel Advisors LLC Q2 2026	BUYNEW	88.15 K	2.95 M	+88.15 K	+0.0%	0.00%
HS Hussman Strategic Advisors, Inc. Q2 2026	SELL	63.00 K	2.11 M	+-42.00 K	-16.4%	0.49%
MM Millennium Management LLC Q2 2026	SELL	50.56 K	1.69 M	+-73.54 K	-43.2%	0.00%
RT Renaissance Technologies LLC Q2 2026	BUY	41.42 K	1.39 M	+3.72 K	+53.1%	0.00%
BH Brevan Howard Capital Management LP Q2 2026	BUYNEW	29.45 K	986.35 K	+29.45 K	+0.0%	0.01%
AC Aqr Capital Management LLC Q2 2026	BUY	15.40 K	515.65 K	+22.00	+39.6%	0.00%
MG Man Group Plc Q2 2026	SELL	11.47 K	384.10 K	+-389.00	+34.8%	0.00%