Lumida
/UPB
⌘K
Upstream Bio Inc

Upstream Bio Inc

UPB
$5.73USD-0.35%-0.02 today

MARKET CAP

313.8M

P/E (TTM)

FWD P/E

DAY RANGE

$6 – $6

52W RANGE

$6
$34

AI Summary

Stalk
Sell NowMedium

UPB remains entrenched in a Stage 4 decline with price trading below its key moving averages. Medium-term bias is bearish, reinforced by a series of lower highs and lower lows and dynamic resistance at the 9/21 EMAs. Despite extreme oversold readings, recent rallies into EMAs have been rejected, supporting a Sell Now posture. A break and hold above the 21 EMA would invalidate this bearish timing edge.

  • Q2 2026 revenue $0.77M up 82.7% YoY, beat estimates by 15.4%
  • EPS loss narrowed to $0.73 vs $0.78 estimate
  • Q2 2026 net loss of $39.7M with negative earnings yield
Full analysis →

Buying

8

institutions

Selling

4

institutions

New Positions

1

this quarter

Filing Period

Q2 2026

latest 13-F

13-F Holdings

InstitutionActionShares HeldValueChangeChg %Weight
BI

Blackrock, Inc.

Q2 2026

BUY3.75 M25.97 M+382.67 K-14.4%0.00%
MM

Millennium Management LLC

Q2 2026

BUY1.14 M7.91 M+206.45 K-6.2%0.00%
JC

Jpmorgan Chase & Co

Q2 2026

BUY1.01 M7.01 M+549.04 K+72.5%0.00%
WP

Woodline Partners LP

Q2 2026

SELL831.48 K5.75 M+-831.48 K-61.6%0.02%
AC

Aqr Capital Management LLC

Q2 2026

BUY544.87 K3.77 M+472.70 K+480.5%0.00%
PA

Point72 Asset Management, L.P.

Q2 2026

BUY453.01 K3.13 M+263.34 K+83.6%0.00%
RT

Renaissance Technologies LLC

Q2 2026

BUY131.30 K908.60 K+69.20 K+62.6%0.00%
MG

Man Group Plc

Q2 2026

BUY73.82 K510.86 K+52.67 K+168.3%0.00%
BH

Brevan Howard Capital Management LP

Q2 2026

BUYNEW50.37 K348.55 K+50.37 K+0.0%0.00%
CA

Citadel Advisors LLC

Q2 2026

SELL15.00 K103.80 K+-63.50 K-85.3%0.00%
JH

Janus Henderson Group Plc

Q1 2026

SELL0.000.00+-1.53 M-100.0%0.00%
AC

Adar1 Capital Management, LLC

Q2 2026

SELL0.000.00+-35.00 K-100.0%0.00%